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首页- Products - Others - Other Targets - 2-Bromohexadecanoic acid

2-Bromohexadecanoic acid

CAS No. 18263-25-7

2-Bromohexadecanoic acid ( ―― )

产品货号. M21865 CAS No. 18263-25-7

2-Bromohexadecanoic acid is a PPAR┙ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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生物学信息

  • 产品名称
    2-Bromohexadecanoic acid
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    2-Bromohexadecanoic acid is a PPAR┙ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.
  • 产品描述
    2-Bromopalmitic acid (18263-25-7) inhibits protein S-palmitoylation. Blocks palmitic acid-induced increase in cAMP levels in human primary melanocytes expressing the melanocortin-1 receptor which undergoes an essential palmitoylation as a prerequisite for receptor signaling.
  • 同义词
    ――
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ――
  • 研究领域
    ――
  • 适应症
    ――

化学信息

  • CAS Number
    18263-25-7
  • 分子量
    335.32
  • 分子式
    CH3(CH2)13CH(Br)CO2H
  • 纯度
    >98% (HPLC)
  • 溶解度
    ――
  • SMILES
    CCCCCCCCCCCCCCC(C(=O)O)Br
  • 化学全称
    ――

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Tsukamoto et al. (2013), Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells; PLoS One, 8(9) e75831 2. Chen et al. (2017), Palmitoylation-dependent activation of MC1R prevents melanomagenesis; Nature, 549 399
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