2-Bromohexadecanoic acid ( ―― )

产品货号. M21865 CAS No. 18263-25-7

2-Bromohexadecanoic acid is a PPAR┙ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量

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生物学信息

产品名称

2-Bromohexadecanoic acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

2-Bromohexadecanoic acid is a PPAR┙ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.
产品描述

2-Bromopalmitic acid (18263-25-7) inhibits protein S-palmitoylation. Blocks palmitic acid-induced increase in cAMP levels in human primary melanocytes expressing the melanocortin-1 receptor which undergoes an essential palmitoylation as a prerequisite for receptor signaling.
同义词

――
通路

Others
靶点

Other Targets
受体

――
研究领域

――
适应症

――

化学信息

CAS Number

18263-25-7
分子量

335.32
分子式

CH3(CH2)13CH(Br)CO2H
纯度

>98% (HPLC)
溶解度

――
SMILES

CCCCCCCCCCCCCCC(C(=O)O)Br
化学全称

――

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Tsukamoto et al. (2013), Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells; PLoS One, 8(9) e75831 2. Chen et al. (2017), Palmitoylation-dependent activation of MC1R prevents melanomagenesis; Nature, 549 399

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